Frequently asked questions

The 1714® live culture in Zenflore® is a unique bacterial culture that has been clinically studied in people with everyday stress.

Zenflore® is the only product that contains the 1714® live culture. By combining this unique Bifidobacterium longum 1714® culture with specially selected vitamins, Zenflore® helps to support mental performance and fatigue.

The unique culture in Zenflore® is a 'good' bacteria that occurs naturally in the human gut. It is part the Bifidobacteria family, one of the first kinds of bacteria passed by mother to baby at birth.

It is a PrecisionBiotics® which work specifically on the area for which it was developed.

Zenflore® contains the unique Bifidobacterium longum 1714® strains. Other ingredients include: Corn starch, gelling agent: hydroxypropyl methyl-cellulose, nicotinamide (vitamin B3), calcium D-pantothenate (Pantothenic acid / vitamin B5), anti-caking agent: magnesium stearate, cyanocobalamin (vitamin B12), pyridoxine hydrochloride (vitamin B6), riboflavin (vitamin B2), thiamine hydrochloride (vitamin B1), pteroylmonoglutamic acid (folic acid), D-biotin.

A single Zenflore® capsule contains around 1 billion bacteria, or 1 x 10^9 colony forming units (CFUs). The number of bacteria in each capsule has been scientifically studied and chosen for optimal effectiveness. The dose in the capsule remains effective throughout its shelf life.

Take one capsule every day, with or without food. For best results, we recommend taking Zenflore® with water, milk or plant-based milk alternatives, rather than hot drinks and acidic drinks such as fruit juices.

If you find it difficult to swallow the capsule, the capsule can be opened and the contents dispensed and mixed into water, milk or food, and consumed straight away.

Zenflore® stays in your gut for as long as you continue to take it.

It performs it's action in the gut and then will naturally be swept out by regular bowel movements.

As long as you feel the stress triggers are there, taking Zenflore® will provide support for your mind and body during busy and demanding times.

By taking a single capsule of Zenflore® every day you can ensure your gut remains primed. If you miss a dose, take it as soon as you remember.

Our PrecisionBiotics® scientists have developed a convenient, once daily formulation, specially designed to reach the human gut with its properties intact.

PrecisionBiotics® formulations are stable, ensuring that none of our products need refrigeration.

No refrigeration required. Store below 25°C.

For best results we recommend you store Zenflore® securely closed in the original packaging.

Zenflore®, with the natural 1714® culture and specially selected vitamins, has been formulated to provide a solution to help reduce tiredness and fatigue.

Yes, Zenflore® is suitable for those following a vegetarian or vegan diet.

Whilst the raw ingredients in Zenflore® may be suitable for those following a Kosher/Halal diet, the production of Zenflore® has not received Kosher/Halal certification.

A Zenflore® capsule is a size 3 capsule which is 15.7mm x 5.85mm. It is one of the smallest capsule sizes available.

No. 

Yes. The 1714® strain in Zenflore® has been shown to survive when exposed to low pH conditions and concentrations of bile representative of conditions in the gut. In addition, the Bifidobacterium longum 1714® strain was originally isolated from a human bowel.

The Bifidobacterium longum 1714® strain in Zenflore®, can be inactivated by alcohol.

We recommend not drinking alcohol for a few hours after taking Zenflore®.

No. Zenflore® is not a substitute for any medication prescribed for you by your doctor.

Do not discontinue any medication without consulting your doctor.

The raw ingredients contained in Zenflore® are suitable for children over 3 years of age. The size of the capsule is small and therefore we recommend this product is used by children over the age of 12 years. If given to younger children, they should be supervised to prevent choking.

The contents of the Zenflore® capsule can also be dispersed in water or milk, or mixed with food, and consumed immediately.

There are no known adverse interactions of Zenflore® with other food supplements, including vitamin and mineral supplements. Zenflore® contains selected B vitamins, therefore if you are taking a supplement containing B vitamins, or if you have a medical condition, or any other questions about whether Zenflore® is suitable for you, please consult your doctor.

This is a natural food supplement. The 1714® culture in Zenflore® is part the family of bacteria passed by mother to baby at birth, that lives naturally in the human gut.

The recommended dosage of Zenflore® is one capsule per day. This is the dosage that PrecisionBiotics® recommends, and that has been tested and validated in clinical trials.

Yes. Zenflore® contains 1714®, a Bifidobacterium longum culture, which is part of the family of bacteria that is passed to babies from their mothers at birth. These bacteria may also be present in breast milk.

The specially selected 1714® culture in Zenflore® should reach your gut in peak condition within a few hours of taking Zenflore®. During the first two weeks, Zenflore® will begin to gently prime the gut where it is needed. During this time, you may experience mild and temporary changes to your gut habits. When taken every day, you can expect to feel the full effects of Zenflore® within four to eight weeks. We do not recommend making changes to your diet before the gut is primed and has adjusted to taking Zenflore®. We recommend that you speak to a healthcare professional who can best advise you about reintroducing trigger foods whilst taking Zenflore®, in the context of your full medical history.

Dietary FODMAP restriction may affect the balance of the gut microbiome. FODMAPS act as prebiotics by providing a nutrient source for our gut bacteria, so if we deprive these bacteria of these sources of nutrients, we potentially reduce the amount of bacteria in our gut. In particular, research shows a reduction in Bifidobacterium strains with dietary FODMAP restriction (Halmos EP et al. Gut 2015, 64. 93-100).

There are no specific studies involving the Bifidobacterium longum 1714® strain in Zenflore® in people following the low FODMAP diet.

We recommend that you speak to a healthcare professional who can best advise you about taking Zenflore® with a low FODMAP diet, in the context of your full medical history.

Zenflore® contains the natural 1714® strain. This naturally occurring strain belongs to <i>Bifidobacterium longum</i>, a bacterial species that may be passed from mother to baby at birth. The strain was first isolated from a healthy human gut.

Bacteria begin to colonize the gut at birth, with the bacterial profile of an individual being developed in early childhood. Once established, the bacterial profile is very resistant to change. When a supplement containing a bacterial culture is consumed, the colonisation in the gut is temporary. No supplement can cause the bacteria to permanently colonise the gut. They stay in your gut only for as long as you continue to take them. After that, they will be naturally swept out by bowel movements, which is why it is important to continue to take Zenflore® every day to keep your gut primed.

The only way bacterial profile is changed over time is to completely change the diet, e.g. to a more diversified diet containing different vegetables, fruits and grains, which provide food to the bacteria and increases bacterial diversity over a long time period.

PrecisionBiotics® has a unique vision and history. For over 20 years, we have researched bacterial cultures and been at the forefront of human microbiome research

As part of our journey, we are now introducing a new brand identity to reflect our continued commitment to developing precision food supplements focused on your needs and supported by the highest scientific standards. Our brand is 50% beautiful biology, our source of constant inspiration, and 50% healthy lifestyle, our constant goal.

PrecisionBiotics® can help you to take control of your own health by unlocking the power of the human microbiome. We put the ME in your MicrobioME.

Yes, the raw ingredients in Zenflore® are suitable for vegans. Zenflore® does not contain any animal products in the formulation.

The raw materials used for Zenflore® do not contain any of the allergens listed in the Regulation (EU) 1169/2011, and the manufacturing facilities ensure there is no cross contamination from allergens.

Zenflore® contains bifidobacteria which are not associated with the production of histamine. The 1714® strain in Zenflore® does not have the enzyme histadine decarboxylase so it is unable to produce histamine.

The Bifidobacterium longum 1714® strain in Zenflore® can be inactivated by heat.

We recommend taking Zenflore® with cold drinks instead of hot drinks.

Ireland

Zenflore® is available in all good pharmacies and health food stores. If you don't see it ask, at the counter and it will be ordered for you.

UK

Zenflore® is available from PrecisionBiotics.com, Amazon, Holland & Barrett, Medino and Boots.

Zenflore®is not available in the USA. However, the 1714® bacterial culture is available in the Zenbiome®supplement range, which is available in the USA via healthcare practitioners. Zenflore®in the future will be available in the USA. Currently products that contain the Bifidobacterium longum strain 1714® are available via Microbiomelabs and Healthcare practitioners. For more information, please contact microbiomelabs.com/contact.

We are unable to offer shipping outside of our distribution areas. We apologise for any inconvenience.

Zenflore® begins working immediately. The specially selected 1714® strain in Zenflore® should reach your gut in peak condition within a few hours of taking Zenflore®. During the first two weeks, Zenflore® will begin to gently prime the gut where it is needed. When taken every day, you can expect to feel the full effects of Zenflore® within four to eight weeks.

Zenflore® contains the Bifidobacterium longum 1714® strain. This strain is combined with the Bifidobacterium longum 35624® strain in the product Alflorex® Dual Action. Together, these dual strains have been clinically studied in people with IBS. Alflorex® Dual Action has been specifically formulated with these unique PrecisionBiotics® strains and calcium, to support digestive health.

If you have further questions about taking our products for IBS, we recommend that you speak to a healthcare professional, as they will be best placed to support you in the context of your full medical history.

The unique 1714® strain in Zenflore® was discovered and developed by PrecisionBiotics® and has been scientifically studied in partnership with experts from a world-leading centre of research into the microbiome.

Whilst data from long term clinical studies are not available, the bacteria in Zenflore® stay in your gut only for as long as you continue to take it. After that, they will be naturally swept out by bowel movements, which is why it is important to continue to take Zenflore® every day on an ongoing basis to keep your gut primed. Zenflore® is taken on a long-term basis by many people across the world. Ongoing observational data is collected from our real world data programs, which show findings consistent with the clinical studies.

There are no known adverse interactions of Zenflore® with medicines. If you are prescribed antibiotics, it is best to take Zenflore® at a different time of day from the antibiotics because the bacteria in Zenflore® can be inactivated by antibiotics.

If you have a medical condition or have questions about whether Zenflore® is suitable for you, please consult your doctor.

Based on the available information, the use of Zenflore® would not impact on the result of the H pylori test, however specific studies in this area have not been carried out. It is best to discuss this query with a healthcare professional.

If you are prescribed antibiotics, it is best to take Zenflore® at a different time of day from the antibiotics because the bacteria in Zenflore® can be inactivated by antibiotics.

We recommend that people with a compromised immune system take extra care when considering taking products containing bacterial cultures. Whilst the Bifidobacterium longum 1714® bacterial culture in Zenflore® has been shown to be safe in a number of clinical research studies, specific studies have not been carried out in people who are immunocompromised. We would recommend that you speak to a healthcare professional such as your doctor, Oncologist or Dietitian, who will be best placed to advise in the context of you full medical history.

A clinical trial which was carried out in people with ulcerative colitis found that the 36524® strain in Alflorex® Dual Action was safe and did not raise any safety concerns. Clinical trials have not been specifically carried out in people with ulcerative colitis for the 1714® strain in Alflorex® Dual Action. Please speak to your doctor who will be best placed to answer any questions you may have and to advise whether or not Zenflore® is suitable for you, in the context of your full medical history.

As a food supplement, there are no specific contraindications for Zenflore®. However, we recommend that people with a compromised immune system take extra care when considering taking products containing bacterial cultures. Whilst the Bifidobacterium longum 1714® bacterial culture in Zenflore® has been shown to be safe in a number of clinical research studies, specific studies have not been carried out in people who are immunocompromised. We would recommend that you speak to a healthcare professional if you have any medical conditions prior to starting Zenflore®, who will be best placed to advise in the context of you full medical history.

Zenflore® has been specifically developed to reduce fatigue and support mental performance during busy and demanding times.* The unique 1714® culture in Zenflore® was discovered and developed by PrecisionBiotics® and has been scientifically studied in partnership with experts from a world-leading centre of research into the human microbiome. This naturally occurring strain belongs to Bifidobacterium longum, a bacterial species that may be passed from mother to baby at birth. Combined with specially selected B vitamins, Zenflore® has been specially formulated to provide a solution to help support a healthy mind and combat fatigue.*

Food supplements should not be used as substitutes for a varied diet and a healthy lifestyle.

*Pantothenic acid: Contributes to normal mental performance; Biotin, folate, niacin, thiamine, vitamins B6 and B12: Contribute to normal psychological function; Folate, niacin, pantothenic acid, riboflavin, vitamins B6 and B12: Contribute to the reduction of tiredness and fatigue; Biotin, niacin, pantothenic acid, riboflavin, thiamine, vitamins B6 and B12: Contribute to normal energy-yielding metabolism.

The unique 1714® strain in Zenflore® was discovered and developed by PrecisionBiotics® and has been scientifically studied in partnership with experts from a world-leading centre of research into the microbiome. It belongs to the family of bacteria (Bifidobacterium longum) that may be passed naturally from mother to baby at birth. The safety and tolerability of this strain has been confirmed in a number of clinical studies. The strain has been available in Zenflore® for some time and is taken on a long-term basis by many people across the world. Ongoing observational data is collected from our real world evidence programs, which show findings consistent with the clinical studies.

There are no known side effects of taking Zenflore®. It is a food supplement containing bacteria belonging to a species that may be passed naturally from mother to baby at birth, and which may live naturally in the gut. The safety of the bacteria contained in Zenflore® has been confirmed by research studies in humans. During the first few weeks of taking Zenflore®, as the bacteria begin to gently prime the gut, some people may experience mild and temporary changes in their gut.

The safety and tolerability of the bacteria contained in Zenflore® has been confirmed by research studies in humans. During the first few weeks of taking Zenflore®, as the bacteria begin to gently prime the gut, some people may experience mild and temporary changes in their gut. It is normal to experience and temporary changes such as bowel changes, diarrhea, stomach pain, flatulence, gas, constipation. These shouldn't last long, and may be an indication that the bacteria are beginning to take effect. When taken every day, you can expect to feel the full effects of Zenflore® within four to eight weeks. Gastrointestinal changes can also be influenced by a number of factors, including changes to our diet, lifestyle, physical activity, routine and stress, so it may be worth exploring any other factors that could have contributed to these recent changes. If you have any further concerns, we would encourage you to speak to a healthcare professional.

Yes. The special packaging for Zenflore® capsules means that they can travel with you and still keep their qualities.

Tube: For best results, store Zenflore® in the original container with the lid securely closed, at less than 25˚C.

Blister packs: For best results, store Zenflore® in the original blister pack, at less then 25˚C.

Zenflore® should be stored below 25˚C. It has been carefully formulated to be stable at room temperature, and does not need to be refrigerated.

Tube: For best results, store Zenflore® in the original container with the lid securely closed.

Blister packs: For best results, store Zenflore® in the original blister pack.

Our stability testing shows that Zenflore® is stable at temperatures up to 25⁰C for 24 months, and in extreme conditions for up to 6 months. This assures us that, if the products are exposed to hot temperatures for a short period of time, such as during transit, their quality is not affected.

There is only a very small amount of sugar contained in each capsule of Zenflore®. If you have a medical condition or have questions about whether Zenflore® is suitable for you, please consult your doctor.